Lemaire I (1991) Selective differences in macrophage populations and monokine production in resolving pulmonary granuloma and fibrosis. Am J Pathol, 138 487 495.

Cystic fibrosis is an example of a disease where you just have a bad ingredient and you have a disease, and we can actually make a direct correspondence between the ingredient and the disease.

Undergo a medical examination at the expense of the employer even after termination of an employment relationship if he she has earlier performed work in conditions of exposure to carcinogenic substances and factors and dust causing fibrosis.

Begin R, Masse S, Rola Pleszczynski M, Boctor M Drapeau G (1987) Asbestos exposure dose bronchoalveolar milieu response in asbestos workers and the sheep model evidences of a threshold for chrysotile induced fibrosis. In Fisher GL Gallo MA ed. Asbestos toxicity.

Over the last 40 years, recombinant DNA technology has revolutionized numerous industrial sectors, including agriculture and pharmaceuticals. It has enabled the development of vaccines against infectious diseases and drugs that treat non infectious illnesses like diabetes, cancer, cystic fibrosis, psoriasis, rheumatoid arthritis, and some genetic disorders.

But it is widely known that certain mutations can run in families, increasing dramatically the risks of certain diseases for example, breast cancer, sickle cell anemia, and cystic fibrosis. Unfortunately, many human molecular geneticists have abdicated any responsibility for trying to decrease the overall burden of such diseases.

Moreover, biomedical research firms are abandoning certain diseases in order to avoid the large scale trials that they require, focusing instead on orphan diseases like cystic fibrosis, which demand smaller clinical trials that have a higher probability of success, leading to drugs that can cost more than 100,000 annually per patient. But, with insurers and payers worldwide becoming increasingly vigilant about controlling costs, this business model s long term prospects are unclear.