My data indicates that I've got about average risk for developing macular degeneration, a kind of blindness.

In many forms of blindness, like retinitis pigmentosa, or macular degeneration, the photoreceptor cells have atrophied or been destroyed.

(a) Respiratory irritant effects (characterized by localized redness, edema, pruritis and or pain) that impair function with symptoms such as cough, pain, choking, and breathing difficulties are included.

And she told me the nurses hadn't mentioned this that she was blind, that she had been completely blind from macular degeneration for five years.

and many more worldwide who are blind or are facing blindness due to diseases of the retina, diseases like macular degeneration, and there's little that can be done for them.

But Folkman persevered, and eventually he proved that such chemical substances do exist. Today, four decades later, such substances have been used to treat more than 10 million people with neovascular diseases such as macular degeneration and many different forms of cancer.

So what happens when a person gets a retinal degenerative disease like macular degeneration? What happens is is that, the front end cells die, the photoreceptors die, and over time, all the cells and the circuits that are connected to them, they die too.

For example, animal studies may provide useful information in terms of clinical signs of toxicity (dyspnoea, rhinitis etc) and histopathology (e.g. hyperemia, edema, minimal inflammation, thickened mucous layer) which are reversible and may be reflective of the characteristic clinical symptoms described above. Such animal studies can be used as part of weight of evidence evaluation