If you ask, what is the big difference between women and men physiologically?

Because if you don't have that sameness, physiologically, you're going to be sick or you're going to die.

Physiologically, there also are differences on two key hormones testosterone, which is the dominance hormone, and cortisol, which is the stress hormone.

Another finding in the SAGhE study arouses skepticism about a cause and effect relationship between the drug and the increased death rate the mortality came from causes that are mechanistically and physiologically quite different mainly bone cancers, cardiovascular diseases, and cerebrovascular events. A more narrow, unimodal manifestation of toxicity would be more persuasive in establishing causation.