It was a rare gem a brain tumor, hemangioblastoma the gift that keeps on giving.

And once those vessels invade the cancer, it can expand, it can invade local tissues.

And, like a tumor, fat grows when blood vessels grow.

Tumor cells can travel through the blood vessels.

It was a rare gem a brain tumor, hemangioblastoma the gift that keeps on giving.

It's a very, very deadly type of cancer called an angiosarcoma.

In fact, if you actually block angiogenesis and prevent blood vessels from ever reaching cancer cells, tumors simply can't grow up.

16 percent! Meaning that there were these pinpoint tumors in skeletal muscle, but only .16 percent of actual metastases suggesting that maybe skeletal muscle is able to control the angiogenesis, is able to control the tumors recruiting these blood vessels.

But once angiogenesis occurs, cancers can grow exponentially.

But for other tumors and cancer types, the improvements have only been modest.

And the first thing that makes me think is that blood vessels are like highways for the tumor cells.

These cancers include acute lymphoblastic leukaemia acute myelogenous leukaemia chronic lymphocytic leukaemia hairy cell leukaemia non Hodgkin's lymphoma Hodgkin's disease melodysplastic syndrome multiple myeloma retinoblastoma Ewing sarcoma Wilms tumour neuroblastoma sarcoma rhabdomyosarcoma testis tumour and lung cancer.

And the same vessels that are feeding tumors allow cancer cells to exit into the circulation as metastases.

So first of all I thought, you know, Wouldn't it be favorable to cancer getting to skeletal muscle? And as well, cancer tumors require a process called angiogenesis, which is really, the tumor recruits the blood vessels to itself to supply itself with nutrients so it can grow.

We call this antiangiogenic therapy, and it's completely different from chemotherapy because it selectively aims at the blood vessels that are feeding the cancers.

Heart diseases, malignant tumours, cerebro vascular diseases and accidents are still the leading causes of death.

So the surgeon can see inside the patient, through their lens, where the tumor is, where the blood vessels are.

Now, in the lab, we can simulate tumor angiogenesis represented here in a black bar.

And so what we're starting to do is we're starting to inject specially designed markers into the bloodstream that will target the cancer.

And under the microscope, you can see hundreds of these brown staining blood vessels, capillaries that are feeding cancer cells, bringing oxygen and nutrients.

So we created a cocktail of antiangiogenic drugs that could be mixed into his dog food as well as an antiangiogenic cream that could be applied on the surface of the tumor.

Without angiogenesis, the tumor remains the size of a pinpoint and it's not harmful.

(b) Induce cancers, leukaemia, keloids and related afflictions

Dr. Folkman had a theory that the progression of tumors could be arrested by cutting off their source of nourishment. He suggested that tumors emit a substance called tumor angiogenesis factor, which causes surrounding blood vessels to grow toward it, supplying nutrition and removing waste.

Cancer cells mutate and they gain the ability to release lots of those angiogenic factors, natural fertilizer, that tip the balance in favor of blood vessels invading the cancer.

All those tumors have heavy bleeding during periods, abdominal pressure, back pain, frequent urination.

In effect, when we give cancer patients antiangiogenic therapy here, an experimental drug for a glioma, which is a type of brain tumor you can see that there are dramatic changes that occur when the tumor is being starved.

Yet, without a blood supply, most of these cancers will never become dangerous.

William Li presents a new way to think about treating cancer and other diseases anti angiogenesis, preventing the growth of blood vessels that feed a tumor. The crucial first step Eating cancer fighting foods that cut off the supply lines and beat cancer at its own game.

She's also in danger, when she damages this, of bleeding profusely.

Dr. Judah Folkman, who was my mentor and who was the pioneer of the angiogenesis field, once called this cancer without disease.

And we can do this because tumor blood vessels are unlike normal, healthy vessels we see in other places of the body They're abnormal they're very poorly constructed and, because of that, they're highly vulnerable to treatments that target them.

He discovered this, a huge bleeding tumor at the base of Kimbo's penis.

Here's a classic example Rebecca has a benign blood vessel tumor that's growing out through her skull, has obliterated her nose, and she's having difficulty seeing.

But starting in 2004, when antiangiogenic therapies first became available, well you can see that there has been a 70 to 100 percent improvement in survival for people with kidney cancer, multiple myeloma, colorectal cancer, and gastrointestinal stromal tumors.

According to forecasts, however, in addition to the growing incidence of thyroid cancer among persons exposed to radioactive iodine, an increase in the number of cases of other forms of malignant neoplasm and cardiovascular and other non oncological types of disease may be expected in the years immediately ahead.

Blood. The blood flowing in my veins

And bone marrow is actually what we use to save the lives of tens of thousands of patients, most of whom have advanced malignancies like leukemia and lymphoma and some other diseases.

Jewish blood in your veins

I had a similar experience when I was working in his lab, trying to isolate the first inhibitors of blood vessel growth (which were large molecular weight substances). This required developing a bioassay that would enable us to observe the inhibition of blood vessel growth in the presence of tumors.

Starting from the age 45 the need of hospital care both among men and women is most often due to cardiovascular diseases and also tumours, diseases connected with the muscular skeletal system and diseases of the connective tissue.

The smallest blood vessels are called capillaries we've got 19 billion of them in our bodies.

This is the blood vessels.

But what's even more interesting from this study is that in those men who did develop prostate cancer, those who ate more servings of tomato sauce actually had fewer blood vessels feeding their cancer.

Therefore, when a tumor comes into skeletal muscle tissue, it can't get a blood supply, and can't grow.