(a) Clarification of the criteria for acute toxicity, reproductive toxicity and target organ systemic toxicity

(k) Toxicity development of a system of rapid monitoring of water toxicity during space flight

3.1.2.5 In footnote 1, replace toxicity class with toxicity Category and Note (e) with Note (f) .

(g) reproductive toxicity (Chapter 3.7). .

3.7.5.1 Decision logic for reproductive toxicity

(a) acute lethality toxicity (Chapter 3.1)

Acute toxicity values are expressed as (approximate) LD50 (oral, dermal) or LC50 (inhalation) values or as acute toxicity estimates (ATE).

The first limitation is the oxygen oxygen toxicity.

He had an oxygen toxicity seizure and he drowned.

In the table for Specific target organ systemic toxicity (single exposure)

Table 3.1.2 In the title, insert for classification after toxicity point estimates .

Chemicals can be allocated to one of five toxicity categories based on acute toxicity by the oral, dermal or inhalation route according to the numeric cut off criteria as shown in the table below.

In the title of the table, replace (approximate) LD50 LC50 with acute toxicity estimates (ATE) .

3.1.2.6.5 In addition to classification for inhalation toxicity, if data are available that indicates that the mechanism of toxicity was corrosivity of the substance or mixture, certain authorities may also choose to label it as corrosive to the respiratory tract.

Did you know rats that ate genetically engineered corn had developed signs of liver and kidney toxicity?

Pursue work to improve further the classification scheme on chronic aquatic toxicity hazards (in cooperation with OECD)

3.8.3.4.5 Care should be exercised when extrapolating toxicity of a mixture that contains Category 3 ingredient(s).

The short answer is They return to the environment in one way or another, continuing the cycle of toxicity.

(a) the acute toxicity estimate (ATE) for the classification of a substance or ingredient in a mixture is derived using

Some reproductive toxic effects cannot be clearly assigned to either impairment of sexual function and fertility or to developmental toxicity.

You die also because oxygen toxicity can cause a seizure makes you convulse underwater, not a good thing to happen underwater.

The work was focused on pathogenicity and toxicity studies, characteristics of agents and methods of their production at the laboratory scale.

In the second sentence of the paragraph, replace specific reproductive toxicity with an adverse effect on sexual function and fertility or on development .

Or someone standing in front of a tank. Or being in a position like Lance Armstrong, and someone says to you, You've got testicular cancer. That's pretty tough for any male, especially if you ride a bike.

But, if we only had an oxygen gas supply cylinder we wouldn't be able to go very deep, because we'd run into oxygen toxicity very, very quickly.

Generally, the hazard posed to people by a small arms ball round that has been fired and is now lying on the ground is negligible (lead toxicity not included).

It's not just my work in amphibians, but similar work has been shown in fish in Europe, holes in the testes and absence of sperm in reptiles in a group from South America and in rats, an absence of sperm in the testicular tubules as well.

The fall of the beryllium reflector parts and partially failed radiation shield of lithium hydride might constitute a threat from the point of toxicity, which would prompt search and clean up (removal) measures.

And the frogs that are exposed to atrazine, the testes are full of holes and spaces, because the hormone imbalance, instead of allowing sperm to be generated, such as in the testis here, the testicular tubules end up empty and fertility goes down by as much as 50 percent.

Furthermore, lower levels of mycotoxins in pest resistant corn mean fewer birth defects, such as spina bifida, and less toxicity to livestock. Such staple food crops also can be modified to contain additional nutrients.

The study focused on saline and sodic lands but other degradation processes of great importance in Kenya include fertility decline, soil acidification and aluminium toxicity, organic matter decline, wind and water erosion, and soil compaction.

For such drugs, reduced consumption is usually aimed at tertiary prevention approaches that highlight the possible negative health consequences related to acute and chronic toxicity that may stem from binging, frequent and continued illicit consumption.

CSTEE (1998) Scientific Committee on Toxicity, Ecotoxicity and the Environment (CSTEE) Opinion on Chrysotile asbestos and candidate substitutes expressed at the 5th CSTEE plenary meeting, Brussels, 15 September 1998 http europa.eu.int comm food fs sc sct out17_en.html

That is, in addition to an appropriate acute toxicity symbol, a corrosivity symbol (used for skin and eye corrosivity) may be added along with a corrosivity hazard statement such as corrosive or corrosive to the respiratory tract. .

Article 11 of the Convention is concerned with the conduct of research and monitoring aimed to improve the basic understanding of such characteristics as the sources, movement, fate, behaviour and toxicity of persistent organic pollutants in the environment.

The military had known for many years that depleted uranium caused heavy metal toxicity to the body, harmed genetic DNA and caused cell mutations resulting in cancer and other disorders as well as birth defects in future generations.

The British pharmaceutical company GlaxoSmithKline recently announced that, together with the US National Institute of Allergy and Infectious Diseases, it is developing an experimental vaccine for Ebola. But it is just entering phase I clinical trials to test toxicity.

From 1998 to 2001, the importation of pesticides of light toxicity (grade IV) (from 64 to 70 ), presenting a lesser health risk, was increased, with a corresponding reduction in the imports of extremely toxic pesticides (from 5 to 3 ).

Women exposed to higher levels of the pesticide DDT before the age of fourteen have a five times higher chances of developing breast cancer when they reach middle age. Could such compounds play a role in unexplained and growing rates of childhood cancer, testicular cancer, and non Hodgkin s Lymphoma throughout the industrial world? Should we wait to find out?

Begin R, Masse S, Rola Pleszczynski M, Boctor M Drapeau G (1987) Asbestos exposure dose bronchoalveolar milieu response in asbestos workers and the sheep model evidences of a threshold for chrysotile induced fibrosis. In Fisher GL Gallo MA ed. Asbestos toxicity.

For warfarin, a widely prescribed drug used to prevent blood clots, genotyping can guide the right dose and hasten the time it takes to get to steady state. Genotyping can also predict severe liver toxicity for drugs such as flucloxacillin or lumiricoxib.

First, new drugs should always offer added value better efficacy, lower toxicity, or greater ease of treatment. Unfortunately, this is not required by current legislation in Europe, where only quality, efficacy, and safety must be demonstrated, without any need for comparative studies.

Research on animals is performed to gain more knowledge about diseases and how to cure them, and to evaluate drugs for toxicity before testing them on humans. In fact, animal studies have played a vital role in almost every major medical advance.

So it's interesting for me, when I'm looking for someone who can really talk to me and talk to an audience about these things, that probably one of the most important people in the world who can discuss toxicity in babies is expert in frogs.

But none of these incidents has acquired the toxicity of the assaults on those deemed insufficiently respectful of the holy cow. Indeed, a signal illiberal achievement of Prime Minister Narendra Modi s BJP regime has been the revival of the cow as an instrument of political warfare.