Neither are other substantial intellectual creations. These skeptics overlook the profound changes that new technologies gradually make in our habits as we discover their possibilities.

That will require both sides to make substantial concessions.

The adoption of this proposal would make it possible to achieve substantial cost savings.

Here are some ways that we can make some dramatic changes.

For instance, substantial changes to tenders after submission, including to their price, and disclosure of tender information, are prohibited (article 34(1)(a) and (8)).

The performance oriented changes embodied in administrative reforms have nearly always been accompanied by budget cuts, downsizing and substantial reorganization of government structures and agencies.

The CD can and must make a substantial contribution to the solution of this problem.

So, if we make no changes today, what does tomorrow look like?

(i) Review and make recommendations to approve changes to OIOS functions, including

The Internet in particular has drastically changed the distribution of tourism products and services and is driving substantial changes in the market structure and consumer behaviour.

Why does this far more substantial minority not make a move to exercise its political muscle?

It was also recognized that changes in the shareholdings of substantial investors should be disclosed to the market as soon as a company becomes aware of them.

But one, to me, that's most compelling is the peculiar sensitivity to small changes that can make large changes in biological development the output.

Other domestic policies such as those on trade, agriculture, environment, research could make substantial contributions to development.

I think that the time is ripe to make fundamental changes in our civilization.

Well, our genes are not our fate, and if we make these changes they're a predisposition but if we make bigger changes than we might have made otherwise, we can actually change how our genes are expressed.

What kind of changes do we need in public policy and funding to make that possible?

And in order for the PSA to go down, they had to make pretty big changes.

So changes that children make in the real world need to translate to the virtual world.

Article 80 In case there are any changes in shareholders during the reporting period, the Company shall make disclosure of the name of new and old shareholders, the date when such changes occur and reasons for such changes, etc.

This has resulted in a substantial and largely irreversible loss in the diversity of life on Earth The changes that have been made to ecosystems have contributed to substantial net gains in human well being and economic development, but these gains have been achieved at the cost of the increasing degradation of many ecosystem services, growing risks of non linear, step changes and the exacerbation of poverty for some groups of people.

Changes had also been made to graduate courses to make them more relevant to national development strategies.

In our opinion, it is necessary and urgent to make changes of that nature to the annual report.

We have to make sure that such reform can keep pace with the changes that have taken place.

Finally, we agree that we should make significant institutional and functional changes to the Commission on Human Rights.

And, again, even this more substantial rise probably represents a substantial underestimate of the increase in the real standard of living. The authorities arrive at their estimates by converting dollar incomes into a measure of real income by using a price index that reflects the changes in the prices of existing goods and services.

Do such post election changes in direction make a mockery of democracy? How can voters make intelligent judgments when campaigns are so carefully scripted and slickly promoted?

As at the world summit, speaker after speaker stressed the need to make faster and more substantial progress towards the Millennium Development Goals.

It is our expectation that in the next six months or so, we will, and must, make substantial progress on management reform issues.

Thirdly, status resolution and the ensuing certainty will mean that we can make faster and more substantial progress on a range of issues.

Her Government would continue to evaluate how it conducted commissions and, when appropriate, make changes to improve the process.

That is a good example of awareness raising within a demanding society on which we have to count in order to make substantial progress.

We believe that the Economic and Social Council, through its ad hoc advisory groups, can make a substantial long term contribution to that effort.

Since then, Japan's initiatives in the field of security will be mainly in the legal system, strategy implementation, policy implementation and other operational level, rather than the substantial adjustments and changes of framework, mechanisms and policies.

These kinds of projections have often been based on simple extrapolations of exponential trends. Over two or three decades, substantial differences in compound growth rates quickly generate huge changes in economic size or per capita income.

Responsibility of the recommending or authorizing international organization cannot arise if, for instance, the recommendation is outdated and not intended to apply to the current circumstances, because of the substantial changes that have intervened since the adoption.

It's simply a question of changing the interface by which people make decisions, and the very nature of the decisions changes.

You can make very small changes in gene code and get really different outcomes, even with the same string of letters.

Then he said, Make a few changes to her throne and let us see whether she will recognize it or not.

Then he said, Make a few changes to her throne and let us see whether she will recognize it or not.

They are supposed to be receptive to new ideas and the adoption of new technologies and are willing to make changes.

For instance, the TIMSS programme prompted the Ministry of Education in Egypt to make changes in curricula and teacher training programmes.

Parties operating under paragraph 1 of Article 5 ( A5 Parties ) have continued to make substantial progress in achieving MB reductions since the previous EC reports(1).

And the paradox is that when you make big changes, you get big benefits, and you feel so much better so quickly.

So all the changes and reforms we were able to make have shown up in results that are measurable in the economy.