They cannot justify developing new drugs unless they can expect to recoup their costs through sales.

Unfortunately, he was smitten in more ways than one, because it made him bankrupt, and he had to tour the world speaking to recoup his money.

Treated waste water and excreta can be considered as a valuable resource with the potential for reuse, and in some cases for sale, with the revenues helping to recoup treatment costs.

Fertilizer and spraying were both more expensive than I thought. While my wheat stalks are sprouting on schedule, I now fear that at harvest time in November prices will fall and I won t recoup my costs.

In the early 1990 s, desperately short of hard currency, Nigeria negotiated contracts permitting the oil companies to develop new fields and recoup their investment before sharing profits. Now, following the companies discovery of massive reserves, technocrats appointed by Yar Adua to take charge of oil policy want Nigeria to get a larger slice of the pie.

Thus, the impact of personalized medicine in the short term might be positive at the patient s bedside, but vast clinical trials to demonstrate the safety of new drugs will impose huge development costs that manufacturers might never recover. (Currently, only about one in five drugs approved by US regulators ever recoup their development costs.) 160 This situation would not be sustainable in the long term.

Thus, the impact of personalized medicine in the short term might be positive at the patient s bedside, but vast clinical trials to demonstrate the safety of new drugs will impose huge development costs that manufacturers might never recover. (Currently, only about one in five drugs approved by US regulators ever recoup their development costs.) This situation would not be sustainable in the long term.